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Table 11 Number of genes in the KEGG DA Pathway, KEGG PD Pathway, and both KEGG DA and PD Pathways in the respective prioritized gene sets

From: Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization

Prioritization
Approach
N n(%) %
DA PD DA-PD DA-PD/DA
ML Limma 246 11(4.47) 6(2.44) 4(1.63) 36.36
ML 168 7(4.17) 5(2.98) 4(2.38) 57.14
Limma 134 9(6.72) 6(4.48) 4(2.99) 44.44
ML ∩ Limma 56 5(8.93) 5(8.93) 4(7.14) 80.00
Only-ML 112 2(1.79) 0(0.00) 0(0.00) 0.00
Only-Limma 78 4(5.13) 1(1.28) 0(0.00) 0.00
Consensus 50 5(10.00) 5(10.00) 4(8.00) 80.00
  1. N: Number of genes prioritized; n: number; %: percentage; DA: genes in the KEGG Dopaminergic Synapse Pathway; PD: genes in the KEGG Parkinson’s Disease Pathway; DA-PD: genes in the KEGG Dopaminergic Synapse Pathway and the KEGG Parkinson’s Disease Pathway
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