Table 11 Number of genes in the KEGG DA Pathway, KEGG PD Pathway, and both KEGG DA and PD Pathways in the respective prioritized gene sets
From: Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization
Prioritization Approach | N | n(%) | % | ||
|---|---|---|---|---|---|
DA | PD | DA-PD | DA-PD/DA | ||
ML ∪ Limma | 246 | 11(4.47) | 6(2.44) | 4(1.63) | 36.36 |
ML | 168 | 7(4.17) | 5(2.98) | 4(2.38) | 57.14 |
Limma | 134 | 9(6.72) | 6(4.48) | 4(2.99) | 44.44 |
ML ∩ Limma | 56 | 5(8.93) | 5(8.93) | 4(7.14) | 80.00 |
Only-ML | 112 | 2(1.79) | 0(0.00) | 0(0.00) | 0.00 |
Only-Limma | 78 | 4(5.13) | 1(1.28) | 0(0.00) | 0.00 |
Consensus | 50 | 5(10.00) | 5(10.00) | 4(8.00) | 80.00 |