Fig. 3
Heat map of correlation between pair of pathways. Legend indicates strength of correlation coefficient (red: high correlation; black: weak correlation). a Heat map of correlation between all pairs of pathways. b Zoom in of block 1 shown in panel a. c Zoom in of block 2 shown in panel a. Pathway names from left to right (bottom to top): 1: Ubiquitin mediated proteolysis, 2: One carbon pool by folate, 3: Wnt signaling pathway, 4: Cell cycle, 5: Hippo signaling pathway, 6: Protein processing in endoplasmic reticulum, 7: MAPK signaling pathway, 8: Lysine degradation, 9: RNA polymerase, 10: N-Glycan biosynthesis, 11: mRNA surveillance pathway, 12: Hedgehog signaling pathway, 13: Dopaminergic synapse, 14: GPI-anchor, 15: RNA degradation, 16: Terpenoid backbone biosynthesis, 17: Mucin type O-Glycan biosynthesis, 18: Rap1 signaling pathway, 19: Adherens junction, 20: Leukocyte transendothelial migration, 21: TGF-beta signaling pathway, 22: Axon guidance, 23: MicroRNAs in cancer, 24: Tight junction, 25: PI3K-Akt signaling pathway, 26: Ras signaling pathway, 27: Chemokine signaling pathway, 28: Serotonergic synapse, 29: Glutamatergic synapse, 30: Cholinergic synapse, 31: Retrograde endocannabinoid signaling, 32: Circadian entrainment, 33: Sulfur relay system, 34: Notch signaling pathway, 35: Alanine, aspartate and glutamate metabolism, 36: Aldosterone-regulated sodium reabsorption, 37: Natural killer cell mediated cytotoxicity, 38: VEGF signaling pathway, 39: Fc epsilon RI signaling pathway, 40: Gap junction, 41: Melanogenesis, 42: FoxO signaling pathway, 43: HIF-1 signaling pathway, 44: Fc gamma R-mediated phagocytosis, 45: Estrogen signaling pathway, 46: Platelet activation, 47: Oxytocin signaling pathway, 48: Vascular smooth muscle contraction, 49: PIP, 50: mTOR signaling pathway, 51: Focal adhesion, 52: Regulation of actin cytoskeleton, 53: Insulin signaling pathway, 54: Thyroid hormone signaling pathway, 55: ErbB signaling pathway, 56: T cell receptor signaling pathway, 57: Neurotrophin signaling pathway, 58: B cell receptor signaling pathway, 59: Prolactin signaling pathway