Skip to main content

Advertisement

Table 1 Genes selected by FEs

From: SFRP1 is a possible candidate for epigenetic therapy in non-small cell lung cancer

  (A) (B) (C) (D)   (A) (B) (C) (D)   (A) (B) (C) (D)
Categorical regression SFRP1 LAMC2
SALL4 SLC16A12      HMGA1
TACSTD1* HOXA5 LAD1    
ANGPT1   KIF1A   PFKFB3  
TACSTD2* H2AFY   DEFB1    
IGSF21      ATP5G2      SRGN  
EFNB1   TM4SF1 UCHL1
MEST GPR56* ALDH3A1
SCG3      S100P EPB41L3  
PCA based unsupervised FE (PC4) PCA based unsupervised FE (PC4) RTN1  
F2R SPINT2 LAMA1  
DKK3 CDH1      
  1. Genes with asterisk were selected by more than one method
  2. (A) Associations with cancer related genes reported by Gendoo server. (B) Significant negative correlations (P < 0.05) between gene expression and promoter methylation. (C) At least one study reported a direct/indirect relationship with NSCLC. (D) At least one study reported a direct/indirect relationship with Wnt/β-catenin signalling pathways. Asterisked three genes are also identified by PCA based unsupervised FE with PC4