Fig. 4

Distribution of ChIP-seq reads around the TSS for gene promoters that are DNA-hypermethylated or unmethylated. Gene promoters were identified as methylated or unmethylated based on the Infinium methylation array data. H3K4me3 a H3K27me3 b sequential-ChIP c and H2A.Z d ChIP-seq reads were binned at 10 bp intervals and the average ChIP-seq reads normalized to corresponding average of the input plotted (Y-axis)