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Table 3 Performance of the 16-gene PAM classifier on the 54 samples

From: Adaptation of a RAS pathway activation signature from FF to FFPE tissues in colorectal cancer

Validation dataset Class Sensitivitya Specificityb LOOCV error rate
Affy FF Mut 0.852 = 23/27 0.778 = 21/27 19 %
NanoS_FFPE Mut 0.704 = 19/27 0.741 = 20/27 28 %
Affy_FFPE Mut 0.519 = 14/27 0.889 = 24/27 30 %
  1. Note: Samples were classified as either KRAS/BRAF mutant (Mut, n = 27) or KRAS/BRAF wild-type (WT, n = 27). Class prediction was performed using the Affy_FF, Affy_FFPE and NanoS_FFPE samples sets
  2. a = number of predicted mutants divided by number of true mutants
  3. b = number of predicted WT divided by number of true WT