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Table 4 The prediction results (for H3N2 in different years)

From: Rules of co-occurring mutations characterize the antigenic evolution of human influenza A/H3N2, A/H1N1 and B viruses

Year Mutations
1973 V78G V242I D275G N188D T122N G144D T155Y R207K L3F   
1976 F3L D73N T83K T126N I217V I278S Q189K S145N    
1978 N53D D193N G158E K50R S137Y M260I D2N V244L G146S I62K  
2001 I226V D133N D124S T121N Y137S R57Q T192I D172E K62E V196A K156Q
2004 V144N A131T E83K R50G W222R V202I G225D H155T H75Q Q156H  
  1. It’s for validation of our method, where ✔ means the site mutation is predicted successfully