Table 2 Molecular profile of GBMsa
From: Computational analysis of the mesenchymal signature landscape in gliomas
Total GBMs | High MS | |
|---|---|---|
Expression subclass | ||
Classical | 39 (25.8%) | 11 (15.9%) |
Mesenchymal | 49 (32.5%) | 38 (55.1%) |
Neural | 26 (17.2%) | 10 (14.5%) |
Proneural | 27 (17.9%) | 9 (13%) |
G-CIMP | 8 (5.3%) | 0 (0%) |
< NA> | 2 (1.3%) | 1 (1.4%) |
MGMT methylation status | ||
Methylated | 53 (35.1%) | 20 (29%) |
Unmethylated | 66 (43.7%) | 31 (44.9%) |
< NA> | 32 (21.2%) | 18 (26.1%) |
IDH mutation status | ||
IDH wt | 140 (92.7%) | 68 (98.6%) |
IDH mut (R132H) | 7 (4.6%) | 0 (0%) |
< NA> | 4 (2.6%) | 1 (1.4%) |