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Table 2 Gene-based association results (p-values) of rare variants (MAF < 5%; SNPs and Indels) of genes near the APOE region with CSF biomarker Aβ1-42 with and without adjusting for APOE genotypes

From: Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Gene SNP + Indel SNP
p-value p-value adjusted for APOE genotype p-value p-value adjusted for APOE genotype
BCL3 8.38E-04 0.0056 7.60E-04 0.0054
CBLC 7.07E-05 0.0011 7.35E-05 0.0013
BCAM 1.97E-04 0.0005 2.49E-04 0.0006
PVRL2 3.55E-05 0.3842 4.40E-05 0.4605
TOMM40 6.84E-07 0.0922 5.01E-07 0.0880
APOE 3.35E-10 0.0039 4.08E-07 0.0036
APOC1 6.18E-11 0.2394 2.85E-11 0.1636
APOC1P1 4.43E-02 0.0145 6.16E-02 0.0097
APOC4 2.11E-02 0.2062 1.60E-02 0.1642
APOC2 2.23E-01 0.5363 1.64E-01 0.5102
CLPTM1 1.02E-02 0.0438 9.12E-03 0.0377
RELB 2.36E-04 0.0053 1.51E-04 0.0042