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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Identification of trunk mutations in gastric carcinoma: a case study

Fig. 4

Mutation frequency distribution in multiregional samples of gastric carcinoma according to mutation types. a Distribution of exonic nonsynonymous mutations in each region of sample with mutation frequency. b Mutation frequencies of all exonic nonsynonymous mutations, classified as private (yellow), branch (blue), and trunk (red) mutations. p1 shows a significant difference between the trunk and private mutations, and p2 shows a significant difference between the trunk and branch mutations. c Mutation frequency of three types of mutations in each sample. Gastric cancer 1 (p1 = 3.5 × 10−6, p2 = 2.4 × 10−4), gastric cancer 2 (p1 = 1.6 × 10−4, p2 = 3.8 × 10−2), gastric cancer 3 (p1 = 6.5 × 10−8, p2 = 1.9 × 10−5), gastric cancer 4 (p1 = 5.4 × 10−5, p2 = 2.7 × 10−3), gastric cancer 5 (p1 = 5.2 × 10−8, p2 = 9.5 × 10−2), gastric cancer 6 (p1 = 8.6 × 10−10, p2 = 9.3 × 10−4). The p values were determined with a Wilcoxon test

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