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Fig. 7 | BMC Medical Genomics

Fig. 7

From: De novo assembly and characterization of breast cancer transcriptomes identifies large numbers of novel fusion-gene transcripts of potential functional significance

Fig. 7

Hierarchical classification system for chimeric transcripts. Chimeric transcripts are depicted as a black-grey box, reference transcripts are represented by blue and green boxes where thick boxes represent open-reading-frames and thin boxes represent 5′ and 3 UTRs. An Inter-genic chimera (a) is defined as a chimeric transcript where components map independently to annotated genes; A ‘gene-desert-I’ chimera (b) is defined as a chimeric transcript where one component maps to a gene-desert region (black box) while the other maps to an annotated gene (green); A ‘gene-desert-II’ chimera (c) is defined as a chimeric transcript where both components map to gene-desert regions. A gene-desert region is defined as the genomic region devoid of any annotated genes within 5 kb of the transcript

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