Fig. 1
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12920-018-0323-4/MediaObjects/12920_2018_323_Fig1_HTML.gif)
Workflow of data analysis for whole-exome sequencing. Workflow shows the steps used to select the significantly altered genes associated with ritodrine-induced side effects from 13 exomes. AF, allele frequency; FDR, false discovery rate; SIFT, sorting intolerant from tolerant