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Fig. 10 | BMC Medical Genomics

Fig. 10

From: Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

Fig. 10

Graphics of the viability test of the three lung cancer cell lines to compound NVP-BEZ235 – the dual inhibitor of PI3K and mTOR. The colored lines represent effects of increasing concentrations of the inhibitors on the survival of three cell lines: sensitive to Nutlin-3 (H1944) and insensitive to Nutlin-3 cell lines (А427 and H292)

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