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Table 6 Subsequent validation performance results of developed neural networks

From: Application of Neural Networks for classification of Patau, Edwards, Down, Turner and Klinefelter Syndrome based on first trimester maternal serum screening data, ultrasonographic findings and patient demographics

Total population Σ Feedforward ANN Feedback ANN
Syndrome Healthy Syndrome Healthy
Healthy 300 36 264 4 296
Syndrome 200 184 16 198 2
Sensitivity [%] 92.00% 99.00%
Specificity [%] 88.00% 98.67%
Average accuracy 89.6% 98.8%