Table 3 Factors for adopting cancer genomics services by category
From: Adopting clinical genomics: a systematic review of genomic literacy among physicians in cancer care
Factors associated with ordering, referring or using genomic sequencing | Studies |
|---|---|
Increases in knowledge, skills, and education | |
Higher genomic confidence | Gray et al. (2014) [21] |
Adequate knowledge of the professional use of predictive testing for breast cancer | Marzuillo et al. (2013) [17] |
Increasing continuing medical education (CME) | Marzuillo et al. (2013) [17] |
Feeling qualified to recommend cancer susceptibility tests (CSTs) | Wideroff et al. (2003) [15] |
Having more than 25% of time allocated to research | Gingras et al. (2016) [16] |
Receiving CSTs educational materials | Wideroff et al. (2003) [15] |
Geographical factors | |
Presence of genetic testing laboratories locally | Marzuillo et al. (2013) [17] |
Practice location in the Northeast | Wideroff et al. (2003) [15] |
Working in Asia | Gingras et al. (2016) [16] |
Practice location in the urban and suburban areas | Koil et al. (2003) [19] |
Patient interests, requests, and health records | |
Family/patient history of cancer | Koil et al. (2003) [19] |
Patient interests | Koil et al. (2003) [19] |
Patient requests for genetic testing | Mazuillo et al. (2013) [17] |
Professional guidelines | |
Endorsement of genomic tests by American Society of Clinical Oncologist (ASCO) professional guidelines | Dressler et al. (2014) [14] |
Having institutional guidelines for molecular sequencing | Gingras et al. (2016) [16] |
Clinical utility and effectiveness of cancer genomics | |
Evidence-based studies demonstrating safety and efficacy of the test | Dressler et al. (2014) [14] |
Prospective clinical trials confirming association of testing with outcome | Dressler et al. (2014) [14] |