Fig. 4From: Impaired type I interferon regulation in the blood transcriptome of recurrent asthma exacerbationsa Gene expression profiles in single AETRI vs. multiple AETRIs. This graph represents the fold change relation between single and multiple AETRIs and identifies two discordant subsets of genes (left upper quadrant and right lower quadrant). The large right lower quadrant includes STAT1. b STAT1 is enriched in the largest discordant set of genes in multiple AETRIs vs. single AETRI. This STAT1 network derived from genes in the right lower quadrant of Fig. 4a represents genes that failed to respond in individuals with multiple AETRIs when compared with single AETRIBack to article page