Identifying statistically significant combinatorial markers for survival analysis

BMC Medical Genomics

Table 4 Number of combinations that are also statistically significant using the validation data

Percentage values indicate the portion of statistically significant combinations from all combinations that can be matched in the data set. ‘High’ results use the binarization similar to our experiment settings where z-scores greater than 2 were set to 1, otherwise, 0. ‘Low’ results consider the case when the genes of interest are all lowly expressed and entries with z-scores less than − 0.5 are set to 1, otherwise, 0. All combinations were tested using these two binarizations, hence, the respective lists of statistically significant combinations found in the validation data may overlap. The ‘Total’ indicates the total number of unique combinations (high or low)that can be matched in the data and the portion of which are statistically significant

ISSN: 1755-8794