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Table 6 The lncRNA-mediated PD-specific miRNAs associated the PD-specific mRNAs identified in our study regulatory network

From: A meta-analysis of public microarray data identifies biological regulatory networks in Parkinson’s disease

Tissue PD-specific miRNA lncRNAs associated the miRNAs the PD-specific mRNAs associated the miRNA TFs associated with the miRNAs
Blood hsa-miR-204-3p LINC00999 HSPA6  
hsa-miR-17-3p RP3-323A16.1, XIST SRPK2 Activation:CCND1,E2F1,MYC, MYCN, NKX2–5, TLX1, TLX3, TNF, ERS1, STAT5;
Repression: NFKB1, SPI1; Neutral: MAPK14
hsa-miR-181a-5p AC000403.4, CASC7, CTB-89H12.4, KCNQ1OT1, LINC00506, N4BP2L2-IT2, RP11-10E18.7, RP11-1134I14.8, RP11-147 L13.14, RP11-314B1.2, RP11-361F15.2, RP11-707A18.1, RP1-309I22.2, ZNF883, ZNRD1-AS1 SRPK2 Neutral: TP63
hsa-miR-181b-5p CASC7, CTB-89H12.4, KCNQ1OT1, RP11-1134I14.8, XIST SRPK2  
hsa-miR-181c-5p CTB-89H12.4, KCNIP4-IT1, KCNQ1OT1, RP11-1134I14.8 SRPK2 Activation: AKT1
hsa-miR-181d   SRPK2  
hsa-miR-19a-3p FAM201A, H19, KCNA3, KCNQ1OT1, LINC00094, RP11-337C18.8, RP11-523G9.3, SNHG14 SRPK2 Activation: E2F1, MYC, MYCN, NKX2–5, TLX1, TLX3, ERS1, STAT5; Repression:SPI1; Neutral:PTEN, MAPK14
hsa-miR-19b-3p CASC7, FAM201A, H19, KCNA3, KCNQ1OT1, LINC00094, RP11-337C18.8, RP11-523G9.3, SNHG14 SRPK2 Activation: E2F1, MYC, MYCN, NKX2–5, TLX1, TLX3, ERS1;
Neutral: MAPK14
hsa-miR-199a-3p CTB-89H12.4, ERVK3–1, XIST NOL7 Neutral: TWIST1
Substantia nigra hsa-miR-93-3p AC012065.7,KCNQ1OT1, LINC00342 SNCA Repression: MYC;
Neutral: E2F1
hsa-miR-153   SNCA  
hsa-miR-23b-3p CASC7,CTC-459F4.3, KCNQ1OT1, RP11-215G15.5, SNHG14, TOB1-AS1, XIST, ZNRD1-AS1 SNCA Repression: MYC;
Neutral: ESR2
hsa-miR-34a-5p AC005154.6, H19, KCNQ1OT1, LINC00674, MIR4697HG, NEAT1, RP11-314B1.2, RP11-582E3.6, RP4-630A11.3, THUMPD3-AS1, TTTY15, TUG1 SNCA Activation: HMGA1, AP-1;
Repression: MYC, NFKB1, YY1, IL-4, PDGF-B, TGFB1;
Neutral: CEBPA
hsa-miR-7-5p CTB-89H12.4, KCNQ1OT1, RP11-273G15.2, RP11-314B1.2, RP11-793H13.8, SNHG14, TSNAX-DISC1, TUG1 SNCA Activation: NFKB1, IL1B, TLR2, TLR4, TLR7,
TLR8, TNF, MYC, NFKB1;
Repression: TLX