Table 1 Clinical characteristics of the study population
From: Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas
Characteristics | mRNA profiling | microRNA profiling | Total subjects | ||||||
|---|---|---|---|---|---|---|---|---|---|
Trisomy 21 (n = 3) | Normal (n = 5) | P value | Trisomy 21 (n = 4) | Normal (n = 5) | P value | Trisomy 21 (n = 7) | Normal (n = 10) | P value | |
Maternal Age (years) | 34.6 ± 3.8 | 37.4 ± 3.9 | 0.853 | 30.3 ± 2.2 | 34.2 ± 3.1 | 0.628 | 32.1 ± 3.6 | 35.8 ± 3.7 | 0.062 |
Gestational age (weeks) | 12.0 ± 0.0 | 12.2 ± 0.4 | 0.092 | 12.2 ± 0.4 | 12.4 ± 0.7 | 0.071 | 12.1 ± 0.4 | 12.3 ± 0.6 | 0.454 |
Body mass index (kg/m2) | 22.3 ± 3.7 | 24.4 ± 6.2 | 0.545 | 21.8 ± 3.3 | 21.5 ± 1.2.2 | 0.874 | 22.0 ± 3.2 | 22.9 ± 4.7 | 0.659 |
Gravidity | 2.7 ± 1.2 | 2.8 ± 0.8 | 0.446 | 1.8 ± 1.0 | 3.0 ± 1.6 | 0.210 | 2.1 ± 1.1 | 2.9 ± 1.2 | 0.201 |
Nuchal translucency (mm) | 3.7 ± 1.4 | 4.9 ± 1.9 | 0.402 | 4.2 ± 0.8 | 3.3 ± 1.5 | 0.377 | 4.0 ± 1.0 | 4.1 ± 1.8 | 0.862 |
Nullipara | 2 | 1 | 0.146 | 2 | 1 | 0.524 | 4 | 2 | 0.162 |
Gender-ratio (female:male) | 1:2 | 1:4 | 1.000 | 1:3 | 1:4 | 1.000 | 2:5 | 2:8 | 1.000 |