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Table 1 Clinical characteristics of the study population

From: Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas

Characteristics mRNA profiling microRNA profiling Total subjects
Trisomy 21 (n = 3) Normal (n = 5) P value Trisomy 21 (n = 4) Normal (n = 5) P value Trisomy 21 (n = 7) Normal (n = 10) P value
Maternal Age (years) 34.6 ± 3.8 37.4 ± 3.9 0.853 30.3 ± 2.2 34.2 ± 3.1 0.628 32.1 ± 3.6 35.8 ± 3.7 0.062
Gestational age (weeks) 12.0 ± 0.0 12.2 ± 0.4 0.092 12.2 ± 0.4 12.4 ± 0.7 0.071 12.1 ± 0.4 12.3 ± 0.6 0.454
Body mass index (kg/m2) 22.3 ± 3.7 24.4 ± 6.2 0.545 21.8 ± 3.3 21.5 ± 1.2.2 0.874 22.0 ± 3.2 22.9 ± 4.7 0.659
Gravidity 2.7 ± 1.2 2.8 ± 0.8 0.446 1.8 ± 1.0 3.0 ± 1.6 0.210 2.1 ± 1.1 2.9 ± 1.2 0.201
Nuchal translucency (mm) 3.7 ± 1.4 4.9 ± 1.9 0.402 4.2 ± 0.8 3.3 ± 1.5 0.377 4.0 ± 1.0 4.1 ± 1.8 0.862
Nullipara 2 1 0.146 2 1 0.524 4 2 0.162
Gender-ratio (female:male) 1:2 1:4 1.000 1:3 1:4 1.000 2:5 2:8 1.000