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Table 2 Expression changes of microRNA and genes showing negative correlation in the T21 placenta

From: Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas

Expression pattern of mRNAs in the T21 placenta Gene Symbol Fold intensity P value FDR Chr microRNAs showing negative correlation
mir Fold intensity P value FDR Chr
Up-regulation DYRK1A 1.530 0.013 0.008 21 mir-188-3p 4.301 0.004 0.007 X
KSR1 1.805 0.013 0.006 17 mir-1301 6.571 0.016 0.046 2
RDH13 1.634 0.016 0.018 19 mir-188-3p 4.301 0.004 0.007 X
SETD4 1.696 0.007 0.009 21 mir-1301 6.571 0.016 0.046 2
TTC3 1.678 0.037 0.045 21 mir-133b 5.470 0.001 0.001 6
U2AF1 1.856 0.007 0.025 21 mir-133b 5.470 0.001 0.001 6
ZNF614 1.615 0.043 0.040 19 mir-188-3p 4.301 0.004 0.007 X
Down-regulation AGA 1.520 0.005 0.002 4 mir-513a-3p 4.192 0.013 0.040 X
C4orf32 1.798 0.017 0.015 4 mir-504, 3.848 0.006 0.012 X
mir-513a-3p 4.192 0.013 0.040 X
mir-891b 4.407 0.014 0.041 X
F2RL1 1.846 0.006 0.004 5 mir-513a-3p 4.192 0.013 0.040 X
mir-1297 8.045 0.012 0.036 13
HGF 2.404 0.020 0.014 7 mir-1297 8.045 0.012 0.036 13
JAM3 1.885 0.032 0.013 11 mir-320c 2.558 0.002 0.002 18
MAP3K5 1.617 0.033 0.029 6 mir-513a-3p 4.192 0.013 0.040 X
mir-891b 4.407 0.014 0.041 X
MRPL43 2.611 0.020 0.016 10 mir-504 3.848 0.006 0.012 X
PHLDA1 1.905 0.027 0.010 12 mir-513a-3p 4.192 0.013 0.040 X
mir-891b 4.407 0.014 0.041 X
mir-1297 8.045 0.012 0.036 13
SUSD2 2.324 0.024 0.008 22 mir-1297 8.045 0.012 0.036 13
TICAM2 1.604 0.043 0.033 5 mir-891b 4.407 0.014 0.041 X
  1. rawP: p value from hypergeometric test, adjP: p value adjusted by the multiple test adjustment