Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas

BMC Medical Genomics

Table 4 Disease association of identified genes

Disease	GeneSymbol	rawP	adjP
Mental Retardation	AGA, DYRK1A, SETD4, TTC3	0.0001	0.0014
Down Syndrome	DYRK1A, SETD4, TTC3	0.0004	0.0028
Trisomy	DYRK1A, TTC3	0.0016	0.0056
Neurobehavioral Manifestations	DYRK1A, SETD4, TTC3	0.0016	0.0056
Chromosome Disorders	DYRK1A, SETD4, TTC3	0.0021	0.0059
Osteoarthritis	F2RL1, JAM3	0.0036	0.0084
Fibrosis	F2RL1, HGF	0.0098	0.0196

rawP: p value from hypergeometric test, adjP: p value adjusted by the multiple test adjustment

ISSN: 1755-8794