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Table 2 CAMP hierarchical clustering results

From: African ancestry is associated with cluster-based childhood asthma subphenotypes

  Cluster 1 (N = 98) Cluster 2 (N = 171) Cluster 3 (N = 544) p-value
Age (years) 7.8 (1.9) 8.7 (2.1) 9.2 (2.1) < 0.0001
Gender No. (%)     0.0675
 Male 50 (51.0) 105 (61.4) 345 (63.4)  
 Female 48 (49.0) 66 (38.6) 199 (36.6)  
Race No. (%)     0.0153
 Caucasian 82 (83.7) 116 (67.8) 359 (66.0)  
 African American 9 (9.2) 25 (14.6) 73 (13.4)  
 Hispanic 5 (5.1) 12 (7.0) 60 (11.0)  
 Other 2 (2.0) 18 (10.5) 52 (9.6)  
BMIZ 0.7 (1.0) 0.6 (1.1) 0.5 (1.0) 0.0929
Age of onset (years) 2.4 (2.2) 2.8 (2.2) 3.2 (2.5) 0.0017
FEV1 PC20 meth (mg/ml) 2.9 (2.8) 1.8 (2.2) 2.0 (2.4) 0.0005
FEV1 percent predicted 96.3 (14.5) 95.0 (14.5) 92.4 (13.9) 0.0117
FVC percent predicted 103.5 (14.3) 104.1 (13.6) 103.6 (12.7) 0.895
FEV1/FVC ratio 82.9 (7.0) 80.6 (8.2) 78.7 (8.3) < 0.0001
Bronchodilator percent change 7.3 (6.9) 11.4 (10.1) 11.1 (10.1) 0.0012
Blood eosinophils (mm3) 228.9 (197.9) 579.7 (442.4) 504 (408.8) < 0.0001
IgE (ng/ml) 200.5 (449.1) 1579 (2624.2) 1161 (2022.7) < 0.0001
Average AM peak flow (L/min) 230.9 (55) 249.8 (67.5) 254.8 (64.4) 0.0040
Average AM symptoms 0.52 (0.40) 0.61 (0.46) 0.63 (0.45) 0.100
Environmental smoke No. (%) 42 (42.9) 60 (35.1) 237 (44.1) 0.1291
In utero smoke No. (%) 19 (19.4) 11 (6.4) 77 (14.2) 0.0046
Atopic dermatitis No. (%) 15 (15.3) 167 (97.7) 17 (3.1) < 0.0001
Positive SPT No. (%) 1 (1) 171 (100) 544 (100) < 0.0001
  1. Mean and SD for continuous variables and No. (%) for categorical variables