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Table 4 Association between subphenotypes and number of prednisone bursts and any ER visit or hospitalizations since last visit

From: African ancestry is associated with cluster-based childhood asthma subphenotypes

Number of prednisone bursts since last visit
CAMP
Predicted number of event Incident rate ratios
Subphenotype Estimate (95% CI) p-value Subphenotypes IRR (95% CI) p-value
 1 0.10 (0.08, 0.13) < 0.0001 2 vs. 1 2.63 (1.45, 2.70) < 0.0001
 2 0.20 (0.16, 0.24)   3 vs. 1 2.04 (1.56, 2.70) < 0.0001
 3 0.20 (0.18, 0.22)   3 vs. 2 1.02 (0.83, 1.27) 0.8153
CARE
Predicted number of event Incident rate ratios
Subphenotype Estimate (95% CI) p-value Subphenotypes IRR (95% CI) p-value
 1 0.08 (0.05, 0.14) 0.3534 2 vs. 1 0.93 (0.57, 1.54) 0.7880
 2 0.08 (0.05, 0.12)   3 vs. 1 1.19 (0.76, 1.89) 0.4420
 3 0.10 (0.07, 0.14)   3 vs. 2 1.28 (0.90, 1.82) 0.1666
Any ER visit or hospitalizations since last visit
CAMP
Predicted probability Odds ratios
Subphenotype Estimate (95% CI) p-value Subphenotypes OR (95% CI) p-value
 1 0.03 (0.02, 0.04) 0.1232 2 vs. 1 1.52 (0.95, 2.44) 0.0776
 2 0.04 (0.03, 0.05)   3 vs. 1 1.54 (1.01, 2.33) 0.0434
 3 0.04 (0.03, 0.04)   3 vs. 2 1.01 (0.75, 1.37) 0.9474
CARE
Predicted probability Odds ratios
Subphenotype Estimate (95% CI) p-value Subphenotypes OR (95% CI) p-value
 1 0.02 (0.01, 0.05) 0.0155 2 vs. 1 0.35 (0.13, 0.98) 0.0458
 2 0.01 (0.004, 0.02)   3 vs. 1 1.20 (0.56, 2.63) 0.6296
 3 0.03 (0.02, 0.04)   3 vs. 2 3.45 (1.47, 7.69) 0.0039