Fig. 3

CD4+ cell (a) and CD8+ cell (b) polynomial regression. A polynomial model, with weight-normalised steroid dosage included as a fixed effect, was used to examine transcript expression over the duration of the study. Top transcripts with statistically significant expression profiles over the duration of the study are shown. The x-axis shows the duration of the study in months and the y-axis shows normalised expression levels (cpm). The red points represent the samples taken from steroid-naive individuals, and the gold points represent the samples taken from individuals who had suffered a relapse at the corresponding time point. The blue line shows the modelled expression values