|
SNP
|
EA
|
Chr
|
Gene/nearest gene
|
Location
|
WHO 1999
|
WHO 2013
|
n
|
|---|
|
OR
|
CI(lower)
|
CI(upper)
|
p-value
|
n
|
OR
|
CI(lower)
|
CI(upper)
|
p-value
|
|---|
|
rs13266634a
|
T
|
8
|
SLC30A8
|
coding-missense
|
1.24
|
1.01
|
1.53
|
0.037
|
2834
|
1.049
|
0.91
|
1.21
|
0.50
|
3837
|
|
rs11605924
|
A
|
11
|
CRY2
|
intron
|
0.84
|
0.71
|
0.99
|
0.038
|
2833
|
1.005
|
0.91
|
1.10
|
0.91
|
3848
|
|
rs35767
|
T
|
12
|
IGF1
|
nearGene-5
|
1.26
|
1.00
|
1.60
|
0.054
|
2837
|
1.15
|
0.98
|
1.33
|
0.07
|
3848
|
|
rs5219a
|
T
|
11
|
KCNJ11
|
coding -missense
|
1.18
|
1.00
|
1.40
|
0.059
|
2605
|
1.00
|
0.91
|
1.11
|
0.91
|
3539
|
|
rs11708067a
|
G
|
3
|
ADCY5
|
intron
|
1.11
|
0.86
|
1.44
|
0.42
|
2810
|
1.25
|
1.09
|
1.45
|
0.002
|
3816
|
|
rs689a
|
A
|
11
|
INS
|
Promoter/intron
|
0.91
|
0.64
|
1.29
|
0.60
|
2835
|
0.81
|
0.65
|
1.00
|
0.054
|
3842
|
|
rs8108269
|
G
|
19
|
GIPR
|
intergenic
|
1.14
|
0.94
|
1.36
|
0.17
|
2568
|
1.12
|
0.99
|
1.25
|
0.059
|
3449
|
|
rs7756992a
|
G
|
6
|
CDKAL1
|
intron
|
0.96
|
0.76
|
1.19
|
0.69
|
2670
|
2.80
|
1.00
|
7.87
|
0.049
|
3626
|
- aindicates loci previously associated with GDM / T2D in India or GDM in studies based on the European population
- Logistic regression was performed on GDM cases diagnosed according to WHO1999 and WHO2013 criteria against controls who had no GDM diagnosis using either criteria
- significant p values where p < 0.05 are indicated in bold
