Table 3 Information on biological processes based on Gene ontology. Up-regulated proteins identified by proteomic analysis of positive lymph node samples. Proteins are referenced by their HGNC gene symbol
From: Differentially expressed proteins in positive versus negative HNSCC lymph nodes
Biological process | Up-regulated proteinsa |
|---|---|
Angiogenesis | HSPB1 |
Apoptosis | LGALS1, S100A9, SFN |
 Anti-apoptosis | ANXA1, GSTP1, HSPB1 |
Autophagy | S100A9 |
Cell adhesion | |
 Cell-cell adhesion | APOA1, POSTN |
Cell communication | |
 Signaling | ANXA1, APOA1, HSPB1, IGHG1, IGKC, LGALS1, S100A7, S100A9, SFN |
 Cell-cell signaling | S100A9 |
Cell growth | |
 Positive regulation of cell growth | S100A9 |
Cell migration or movement | |
 Cell motility | ANXA1, HSPB1, S100A9 |
Cytoskeleton organization | KRT13, S100A9 |
Developmental process | |
 System development | GSTP1, POSTN |
 Cell differentiation | ANXA1 |
 Epidermis development | FABP5, S100A7, SFN |
Metabolic process | AKR1B10, APOA1, FABP5, GSTP1 |
 Protein metabolic process | APOA1, CSTB |
 Lipid metabolic process | APOA1, FABP5 |
 Protein modification process | GSTP1, SFN |
Response to stimulus | ANXA1, HSPB1 |
 Defense response | KRT6A, S100A7, S100A9 |
 Inflammatory response | ANXA1, APOA1, S100A9 |
 Immune response | APOA1, IGHG1, IGKC |
 Response to ROS | GSTP1, S100A7 |
Transcription | S100A9, SFN |
Translation | HSPB1 |
Transport | APOA1 |