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Table 1 Genes with common variants (MAF < 10%) in all the members of a subgroup

From: Whole exome sequencing in adult-onset hearing loss reveals a high load of predicted pathogenic variants in known deafness-associated genes and identifies new candidate genes

Gene Sub-group Number of variants Type of variants
TTN Recessive 22 Non-synonymous
MON1B Metabolic 1 Frameshift
NEDD4 Sensory 2 Non-synonymous
ZAN Sensory 7 Six non-synonymous, one in-frame deletion
  1. Details of the four genes found to be mutated in all members of a subgroup. TTN (underlined) is a candidate for exclusion