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Table 2 C-index of the Cox proportional hazards models based on different features

From: Toward the precision breast cancer survival prediction utilizing combined whole genome-wide expression and somatic mutation analysis

Feature type Features C-index P-value
Gene expression 330 significant univariate genes 0.584 0.0011
118 significant univariate genes with hazard ratio > 1.221 0.636 <  0.0001
88 significant univariate genes selected by GA 0.656 <  0.0001
Somatic mutation 25 functional annotations 0.603 0.0012
15 gene ontology terms 0.567 0.0013
14 pathways 0.548 0.0037
54 functional gene sets combining functional annotations, GO terms and pathways 0.591 0.0016
Gene expression & somatic mutation All 142 features (88 significant univariate genes and 54 functional gene sets) 0.658 <  0.0001