Fig. 3

After integration, 7977/26,868 genes were identified as highly desirable. All genes in the iR-none analysis were sorted from most desirable (rank = 1) to least desirable (rank = 26,868) and plotted according to their overall desirability scores, ranging from 8.04E-16 to 0.46. Because this analysis included 10 omics studies, the normalized lower bound for our set of ‘desirable’ candidate genes is 0.1 (blue line) and 7977 genes achieved scores greater than or equal to that value. Furthermore, the results of our permutation test are plotted in pink, with a mean of 0.059 (95% CI [0.058, 0.061]). All desirability scores for the entire data set are available in Additional file 2 (and in Additional files 3 and 7 for iR-num and iR-per, respectively)