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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities

Fig. 2

Convergent downstream genetic mechanisms predicted from shared eQTL RNA between disease-pairs are enriched among comorbidities observed in clinical datasets. Vertical axis = odds ratio of overrepresentation of shared molecular mechanisms among clinical comorbidities (Results-Convergent genetic mechanisms between disease-pairs are enriched among comorbid disease). Left bottom axis = FDR cutoffs of comorbidities found in the HCUP clinical datasets (OR > 3; Results- Prioritized comorbidities), right bottom axis = FDR cutoffs of shared molecular mechanisms discovered between two diseases

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