Fig. 1
From: Discovering functional impacts of miRNAs in cancers using a causal deep learning model
Illustration of the mCADET model. a An example of the causal relationship between high correlated miRNA-mRNA pairs. The triangles represent miRNAs. The pentagons represent mRNAs and the circles represent hidden regulators. b mCADET model with edges added from observed miRNA (visible units) to observed mRNA (visible units) to reflect the regulatory role of miRNA on the expression of mRNA. c Semi-RBM positive phase d Semi-RBM negative phase. Solid lines represent the update for miRNAs and dotted lines represent the update for mRNAs