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Table 3 Analytical Precision

From: Analytical validation of a prognostic prostate cancer gene expression assay using formalin fixed paraffin embedded tissue

Sample Model Mean Day SD (95% CI) Run SD (95% CI) Equipment SD (95% CI) Reagent Lot SD (95% CI) Operator SD (95% CI) Within Run SD (95% CI) Total SD (95% CI)
ES-2 cell line 1.418 0 (0, 0.006) 0 (0, 0.002) 0 (0, 0.002) 0 (0, 0.002) 0 (0, 0.007) 0.014 (0.011, 0.015) 0.014 (0.012, 0.016)
Assay Negative −0.123 0.010 (0, 0.024) 0.006 (0, 0.014) 0.014 (0, 0.022) 0.010 (0, 0.017) 0.016 (0, 0.021) 0.027 (0.022, 0.033) 0.038 (0.031, 0.048)
Medical Decision Point 0.307 0 (0, 0.022) 0.010 (0, 0.016) 0.010 (0, 0.016) 0.013 (0, 0.022) 0.015 (0, 0.020) 0.032 (0.026, 0.039) 0.040 (0.035, 0.053)
Assay Positive 1.090 0 (0, 0.014) 0.008 (0, 0.011) 0.008 (0, 0.012) 0.009 (0, 0.013) 0.007 (0, 0.009) 0.019 (0.015, 0.023) 0.025 (0.021, 0.031)
  1. Model mean and standard deviation (SD) point estimates from nested linear mixed model. CI confidence interval