Table 4 Pathway analysis for the 41 mRNA biomarkers
Pathway ID | Pathway Name | Molecule | AE |
|---|---|---|---|
1,430,728 | Metabolism | DTYMK;DBH;HADHA;KYNU;SRD5A2 | 5 |
109,582 | Hemostasis | F11;SOD1;SLC3A2 | 3 |
1,640,170 | Cell Cycle | CDK4;NUF2;TAOK1 | 3 |
69,278 | Cell Cycle, Mitotic | CDK4;NUF2;TAOK1 | 3 |
74,160 | Gene Expression | NR1I2;RPSA;F11 | 3 |
162,582 | Signal Transduction | HEBP1;SPP1 | 2 |
1,643,685 | Disease | SPP1;RPSA | 2 |
200,050 | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | CDK4;SLC3A2 | 2 |
200,170 | Nongenotropic Androgen signaling | SHBG;PELP1 | 2 |
212,436 | Generic Transcription Pathway | NR1I2;F11 | 2 |
382,551 | Transmembrane transport of small molecules | FLVCR1;SLC3A2 | 2 |
453,277 | Mitotic M-M/G1 phases | NUF2;TAOK1 | 2 |
556,833 | Metabolism of lipids and lipoproteins | HADHA;SRD5A2 | 2 |
68,877 | Mitotic Prometaphase | NUF2;TAOK1 | 2 |
68,886 | M Phase | NUF2;TAOK1 | 2 |
69,306 | DNA Replication | NUF2;TAOK1 | 2 |
71,291 | Metabolism of amino acids and derivatives | DBH;KYNU | 2 |
hsa00380 | Tryptophan metabolism | KYNU;HADHA | 2 |
hsa04010 | MAPK signaling pathway | MAPKAPK5;TAOK1 | 2 |
hsa04142 | Lysosome | CTSO;CTSO | 2 |
hsa04510 | Focal adhesion | SPP1;MYLK | 2 |
hsa04620 | Toll-like receptor signaling pathway | SPP1;CTSO | 2 |