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Table 3 Top 15 GOs by BaseSpace Correlation Engine

From: Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid

Biogroups

direction

P-value

ligase activity

down

1.60E-09

ligase activity, forming carbon-nitrogen bonds

down

2.30E-09

acid-amino acid ligase activity

down

4.40E-09

kinase binding

down

5.10E-09

response to oxidative stress

down

5.90E-09

mitochondrial inner membrane

down

1.40E-07

cellular component biogenesis at cellular level

down

3.30E-07

DNA catabolic process

down

4.80E-07

protein binding transcription factor activity

down

6.90E-07

transcription cofactor activity

down

1.30E-06

ubiquitin-protein ligase activity

down

1.50E-06

response to hypoxia

down

1.90E-06

response to decreased oxygen levels

down

2.10E-06

transcription factor binding transcription factor activity

down

2.20E-06

negative regulation of cysteine-type endopeptidase activity

down

2.80E-06

  1. Enrichment of Gene Ontology (GO) in DEGs was analyzed by BaseSpace Correlation Engine. The top 15 ranked biogroups are listed