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Table 4 Univariate and multivariate analysis of OS predictors of patients with DLBCL

From: Clinical aspects of TP53 gene inactivation in diffuse large B-cell lymphoma

 

HR

95% CI

P-value

Univariate analysis

 B-symptoms

2.401

0.530–0.876

0.256

 Performance score 2–3

1.938

0.905–4.149

0.088

 Stage III-IV

2.025

0.576–7.116

0.271

 Extranodal foci

3.233

1.140–9.951

0.029

 Bone marrow involvement

1.539

0.501–4.722

0.451

 Elevated S-LDH

1.073

0.900–9.438

0.068

 IPI score > 2

2.844

1.384–5.842

0.004

 TP53mut

2.707

1.077–6.800

0.034

Multivariate analysis

 IPI score > 2

2.994

1.405–6.381

0.005

 TP53mut

2.128

0.627–7.217

0.226

 Extranodal foci

2.405

0.787–7.369

0.125

  1. Abbreviations: S-LDH serum lactate dehydrogenase, IPI International Prognostic Index, HR hazard ratio, CI confidence interval