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Table 4 Univariate and multivariate analysis of OS predictors of patients with DLBCL

From: Clinical aspects of TP53 gene inactivation in diffuse large B-cell lymphoma

  HR 95% CI P-value
Univariate analysis
 B-symptoms 2.401 0.530–0.876 0.256
 Performance score 2–3 1.938 0.905–4.149 0.088
 Stage III-IV 2.025 0.576–7.116 0.271
 Extranodal foci 3.233 1.140–9.951 0.029
 Bone marrow involvement 1.539 0.501–4.722 0.451
 Elevated S-LDH 1.073 0.900–9.438 0.068
 IPI score > 2 2.844 1.384–5.842 0.004
TP53mut 2.707 1.077–6.800 0.034
Multivariate analysis
 IPI score > 2 2.994 1.405–6.381 0.005
TP53mut 2.128 0.627–7.217 0.226
 Extranodal foci 2.405 0.787–7.369 0.125
  1. Abbreviations: S-LDH serum lactate dehydrogenase, IPI International Prognostic Index, HR hazard ratio, CI confidence interval