The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins

Table 1 Proteins with statistically significant differences (p-value< 0,05) between points of blood collection

Protein name	Means, fmol/μl			p-values			МW (kDa)
Protein name	L-30	R + 1	R + 7	L-30 vs R + 1	R + 1 vs R + 7	L-30 vs R + 7	МW (kDa)
78 kDa glucose-regulated protein	6.3	4.6	5.3	0.031	0.216	0.200	72.3
Alpha-2-HS-glycoprotein	134.2	80.3	86.3	0.037	0.794	0.215	39.3
Apolipoprotein A-II	5168.8	4188.9	4410.8	0.015	0.423	0.038	11.2
Apolipoprotein A-IV	1277.7	1002.1	1425.1	0.067	0.003	0.275	45.4
Apolipoprotein C-III	8.1	6.7	8.3	0.121	0.031	0.850	10.9
Beta-2-microglobulin	110.6	96.6	116.8	0.024	0.004	0.322	13.7
Cadherin-5	16.2	14.2	15.7	0.044	0.193	0.635	87.5
cDNA FLJ53327	1007.1	802.2	959.2	0.012	0.048	0.535	77.8
Cystatin-C	71.9	41.9	49	0.014	0.630	0.218	15.8
Fibronectin	121.8	100.9	110.9	0.044	0.145	0.267	262.6
Fibulin-1	139.9	129.2	163.8	0.213	0.000	0.021	77.2
Gelsolin	811.6	611.1	737.2	0.001	0.005	0.182	85.7
Insulin-like growth factor binding protein, acid labile subunit	155.6	153.5	142.5	0.703	0.047	0.014	66.1
Lumican	510.3	446.9	528.2	0.028	0.001	0.503	38.4
Mannan-binding lectin serine protease 1	67.4	59.5	56.3	0.063	0.459	0.010	79.2
Neuropilin-2	42.7	41.1	46.8	0.432	0.016	0.106	104.9
Plasma serine protease inhibitor (PAI-3)	89.9	91.8	104.7	0.783	0.045	0.079	45.7
Protein S100-A9	2.7	6.2	3.8	0.039	0.070	0.152	13.2
Serotransferrin	9743.3	8235.4	8343.3	0.028	0.843	0.030	77.1

ISSN: 1755-8794