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Table 2 Proteins with increased or stable concentration at R + 1

From: The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins

Protein name Means, fmol/μl Complement component Acute phase proteins Proteases Protease inhibitors
L-30 R + 1 R + 7
Alpha-1-antichymotrypsin 2392.5 2411.6 2473.1   +   +
Apolipoprotein B-100 474.9 478.1 415.9     
Apolipoprotein E 797.9 914.5 915.8     
Beta-2-glycoprotein 1 3367.2 3387.3 3471.1     
C4b-binding protein alpha chain 208.1 208.9 211.1     
Carbonic anhydrase 1 55.4 69.9 56.8     
Ceruloplasmin 2158.3 2182.9 2292.2   +   
Coagulation factor XI 46.9 49.3 46.2 +   +  
Complement C2 108.4 109.5 110.0 +   +  
Complement C3 5936.4 5986.7 6141.2 + + +  
Complement C4-B 1639.5 1651.7 1691.3 +   +  
Complement component C9 215.0 252.3 247.2 + +   
Fibrinogen alpha chain 6781.9 7651.4 7726.8 + +   
Fibrinogen beta chain 419.0 423.5 428.7 + +   
Fibrinogen gamma chain 426.4 480.3 490.1 + +   
Fibrinopeptide A 1469.0 1593.3 1663.9     
Haptoglobin 18,033.4 19,230.8 19,612.7   + +  
Hemoglobin subunit alpha 2628.5 3248.1 2452.5     
Insulin-like growth factor-binding protein complex acid labile subunit 143.3 156.9 148.1     
Leucine-rich alpha-2-glycoprotein 271.2 321.2 308.2     
Lipopolysaccharide-binding protein 121.1 126.8 119.4   +   
MRNA for apolipoprotein E 677.4 790.8 778.8     
Plasma serine protease inhibitor (PAI-3) 89.9 91.8 104.7 +    +
Protein AMBP 926.0 1007.6 1080.5     +
Protein S100-A9 2.7 6.2 3.8     
Serum paraoxonase/lactonase 3 20.0 20.2 18.8     
Thyroxine-binding globulin 166.9 173.6 171.6     +
Vitamin D-binding protein 3222.1 3301.9 3306.5     
Vitamin K-dependent protein C 40.4 40.6 41.5 +   +  
Vitronectin 325.1 326.4 352.1     
  1. Note: proteins which continue to increase concentration at R + 7 are bold