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Table 3 The characteristics and BasePhasing results of the patients in this study

From: BasePhasing: a highly efficient approach for preimplantation genetic haplotyping in clinical application of balanced translocation carriers

Sample Karyotype or Grade of blastocysts ASA call rate Karyomap-12 call rate Results of BasePhasing Results of Karyomap-12
Family 1
 Mother 46,XX 0.9862835 0.9842981   
 Father 46,XY,t(1:5)(q21;q35) de novo 0.9897337 0.9838287   
 Embryo-1 4BB 0.9643379 0.9607865 Normal Normal
 Embryo-2 4AB 0.9549406 0.9446636 Normal Normal
 Embryo-3 5BB 0.9460028 0.9430658 Carrier Carrier
 Embryo-4 5AB 0.9454245 0.9396804 Unbalanced Unbalanced
 Embryo-5 5AB 0.9342148 0.9312841 Normal Normal
 Embryo-6 5 BC 0.9626743 0.9603586 Carrier Carrier
 Embryo-7 4BB 0.9572856 0.951569 Unbalanced Unbalanced
 Embryo-8 4 BC 0.9062205 0.8713027 Unbalanced Unbalanced
Family 2
 Mother 46,XX 0.9946477 0.9843602   
 Father 46,XY,t(6;7)(q23;q34) mat 0.9950734 0.9892606   
 Embryo-1 5BB 0.9273288 0.9067822 Normal Normal
 Embryo-2 5AB 0.9126197 0.8760443 Carrier Carrier
 Embryo-3 5AB 0.9505755 0.9167728 Carrier Carrier
 Embryo-4 5BB 0.9222872 0.9001667 Normal Normal
 Embryo-5 5BB 0.9429535 0.9313635 Carrier Carrier
 Embryo-6 5 AC 0.9406152 0.9309729 Unbalanced Unbalanced
 Embryo-7 5 BC 0.9419208 0.9253105 Unbalanced Unbalanced
 Embryo-8 5BB 0.9403009 0.9343323 Unbalanced Unbalanced
 Embryo-9 5 BC 0.9533952 0.945755 Unbalanced Unbalanced
 Embryo-10 5 BC 0.9147238 0.9127144 Unbalanced Unbalanced
  1. Mat: the balanced translocation was inherited from carrier’s mother. The karyotypes were identified by peripheral blood cells