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Table 3 Regions of LCSH considered common (frequency ≥ 5%) identified among 430 CMA results

From: Long contiguous stretches of homozygosity detected by chromosomal microarrays (CMA) in patients with neurodevelopmental disorders in the South of Brazil

Frequencies Chr/Cytobands Initial Position Final Position Size (Kbp)
49% 16p11.2p11.1a,d,e 31,957,367 35,220,544 3.263
21% 1q21.2q21.3d, e 147,215,796 150,287,884 3.072
19% 11p11.2p11.12a, d, e, b 47,178,984 51,550,787 4.371
16% 3p21.31p21.2a, d, e, b 48,712,421 52,852,488 4.140
12% 15q15.2q21.1d 42,423,100 45,726,314 3.303
9% 2q11.1q11.2d, e 95,341,387 98,776,856 3.435
6% 1p33p32.3d, e 49,205,205 53,121,054 3.915
6% 20q11.21q11.23d, c 31,940,638 36,081,725 4.141
5% 10q22.1q23.31d 73,824,169 77,212,167 3.388
5% 6p22.2p22.1d, e, b 26,340,871 30,006,805 3.666
5% 7q11.22q11.23 71,997,278 76,128,151 4.130
  1. When the beginning and/or end of the cytobands were variable, a linear position was obtained based on the median of the beginning or end. All analyses, as well as linear positions, were based on the human reference genome, version GRCh37/hg19
  2. aWang et al. 2015
  3. bPajusalu et al. 2015
  4. cLing-Hui et al. 2006
  5. dKearney H. M. (Personal communication, 2017)
  6. eSanchez P. (Personal communication, 2017)
  7. The underlined LCSH was only found in our study