Long contiguous stretches of homozygosity detected by chromosomal microarrays (CMA) in patients with neurodevelopmental disorders in the South of Brazil

Table 3 Regions of LCSH considered common (frequency ≥ 5%) identified among 430 CMA results

Frequencies	Chr/Cytobands	Initial Position	Final Position	Size (Kbp)
49%	16p11.2p11.1^a,d,e	31,957,367	35,220,544	3.263
21%	1q21.2q21.3^{d, e}	147,215,796	150,287,884	3.072
19%	11p11.2p11.12^{a, d, e, b}	47,178,984	51,550,787	4.371
16%	3p21.31p21.2^{a, d, e, b}	48,712,421	52,852,488	4.140
12%	15q15.2q21.1^d	42,423,100	45,726,314	3.303
9%	2q11.1q11.2^{d, e}	95,341,387	98,776,856	3.435
6%	1p33p32.3^{d, e}	49,205,205	53,121,054	3.915
6%	20q11.21q11.23^{d, c}	31,940,638	36,081,725	4.141
5%	10q22.1q23.31^d	73,824,169	77,212,167	3.388
5%	6p22.2p22.1^{d, e, b}	26,340,871	30,006,805	3.666
5%	7q11.22q11.23	71,997,278	76,128,151	4.130

When the beginning and/or end of the cytobands were variable, a linear position was obtained based on the median of the beginning or end. All analyses, as well as linear positions, were based on the human reference genome, version GRCh37/hg19
^aWang et al. 2015
^bPajusalu et al. 2015
^cLing-Hui et al. 2006
^dKearney H. M. (Personal communication, 2017)
^eSanchez P. (Personal communication, 2017)
The underlined LCSH was only found in our study

ISSN: 1755-8794