Skip to main content
Fig. 5 | BMC Medical Genomics

Fig. 5

From: Structural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sézary syndrome, and HIV infection

Fig. 5

Copy number of pericentromeric K222 in cancer, HIV, and control subjects. The proviral copy number of K222 was quantitated by qPCR using the primers K222F and K222R, and the molecular probe K222P, which specifically detect K222 and no other HERV-K proviruses. The copy number of K222 was calculated in the DNA of the PBLs of control subjects, patients with CTCL, breast cancer (BC), diffuse large B cell lymphoma (DLBCL), follicular lymphoma (FL), and HIV. The copy number is an estimate of the approximate number of copies per genome and was normalized to the levels of gapdh as described in the methods section. No significant differences were observed in the mean copy number of K222 in cancer or HIV patients as compared to the control subjects. ns = not significant

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us