Structural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sézary syndrome, and HIV infection

Table 1 Frequency of Detection of K111 in DNA from Cutaneous T-cell Lymphoma (CTCL) patients

Disease	No. tested	−/− K111	Frequency of −/− K111 (%)	X ²	p value
CTCL Total	35	13	37.14	6.96	0.0083
CTCL	13	4^b	30.7	0.32	ns
CTCL + LCT	11	4^c	36.4	2.97	0.0423
Sézary Syndrome	11^a	5	45.5	4.260	0.0390
Caucasian CTCL	35	13	37.1	8.475	0.003601
African American CTCL	4	0	0	24	ns
Caucasian healthy	160	25	15.6

The table shows the frequency of detection of the −/−K111 genotype in patients with CTCL. This proportion is compared to the prevalence of −/−K111 in a population of healthy Caucasian individuals. ^aTwo patients with Sz also developed LCT. Neither of these patients was −/− K111. ^bOne patient developed peripheral T-cell lymphoma and a second patient developed Hodgkin Lymphoma.^cOne patient developed concomitant Hodgkin Lymphoma. LCT Large cell transformation, Sz Sézary Syndrome. p values were calculated using a X² test

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