Table 3 The top 30 genes with the highest scores obtained from the TCGA dataset
Rank | Gene symbol | Entrez Gene Id | Gene Description | Score |
|---|---|---|---|---|
1 | ERBB2 | 2064 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.416 |
2 | STARD3 | 10,948 | StAR-related lipid transfer (START) domain containing 3 | 0.339 |
3 | PGAP3 | 93,210 | post-GPI attachment to proteins 3 | 0.295 |
4 | FOXC1 | 2296 | forkhead box C1 | 0.276 |
5 | CDKN2A | 1029 | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.270 |
6 | ORMDL3 | 94,103 | ORM1-like 3 (S. cerevisiae) | 0.259 |
7 | GSDMB | 55,876 | gasdermin B | 0.245 |
8 | B3GNT5 | 84,002 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.236 |
9 | PSMD3 | 5709 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.235 |
10 | HAPLN3 | 145,864 | hyaluronan and proteoglycan link protein 3 | 0.231 |
11 | CDCA7 | 83,879 | cell division cycle associated 7 | 0.222 |
12 | PSAT1 | 29,968 | phosphoserine aminotransferase 1 | 0.216 |
13 | C17orf37 | 84,299 | migration and invasion enhancer 1 | 0.215 |
14 | GABRP | 2568 | gamma-aminobutyric acid (GABA) A receptor, pi | 0.215 |
15 | TMSB15B | 286,527 | thymosin beta 15B | 0.214 |
16 | MED1 | 5469 | mediator complex subunit 1 | 0.208 |
17 | CDCA2 | 157,313 | cell division cycle associated 2 | 0.207 |
18 | FAM171A1 | 221,061 | family with sequence similarity 171, member A1 | 0.203 |
19 | CCNE1 | 898 | cyclin E1 | 0.197 |
20 | CDK12 | 51,755 | cyclin-dependent kinase 12 | 0.194 |
21 | DSC2 | 1824 | desmocollin 2 | 0.192 |
22 | STAC | 6769 | SH3 and cysteine rich domain | 0.189 |
23 | PADI2 | 11,240 | peptidyl arginine deiminase, type II | 0.189 |
24 | RCOR2 | 283,248 | REST corepressor 2 | 0.179 |
25 | IGF2BP2 | 10,644 | insulin-like growth factor 2 mRNA binding protein 2 | 0.176 |
26 | CDH3 | 1001 | cadherin 3, type 1, P-cadherin (placental) | 0.175 |
27 | ZNF695 | 57,116 | zinc finger protein 695 | 0.175 |
28 | CLCN4 | 1183 | chloride channel 4 | 0.172 |
29 | MEX3A | 92,312 | mex-3 homolog A (C. elegans) | 0.171 |
30 | CBS | 875 | cystathionine-beta-synthase | 0.171 |