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Table 3 The top 30 genes with the highest scores obtained from the TCGA dataset

From: ClearF: a supervised feature scoring method to find biomarkers using class-wise embedding and reconstruction

Rank Gene symbol Entrez Gene Id Gene Description Score
1 ERBB2 2064 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.416
2 STARD3 10,948 StAR-related lipid transfer (START) domain containing 3 0.339
3 PGAP3 93,210 post-GPI attachment to proteins 3 0.295
4 FOXC1 2296 forkhead box C1 0.276
5 CDKN2A 1029 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.270
6 ORMDL3 94,103 ORM1-like 3 (S. cerevisiae) 0.259
7 GSDMB 55,876 gasdermin B 0.245
8 B3GNT5 84,002 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 0.236
9 PSMD3 5709 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.235
10 HAPLN3 145,864 hyaluronan and proteoglycan link protein 3 0.231
11 CDCA7 83,879 cell division cycle associated 7 0.222
12 PSAT1 29,968 phosphoserine aminotransferase 1 0.216
13 C17orf37 84,299 migration and invasion enhancer 1 0.215
14 GABRP 2568 gamma-aminobutyric acid (GABA) A receptor, pi 0.215
15 TMSB15B 286,527 thymosin beta 15B 0.214
16 MED1 5469 mediator complex subunit 1 0.208
17 CDCA2 157,313 cell division cycle associated 2 0.207
18 FAM171A1 221,061 family with sequence similarity 171, member A1 0.203
19 CCNE1 898 cyclin E1 0.197
20 CDK12 51,755 cyclin-dependent kinase 12 0.194
21 DSC2 1824 desmocollin 2 0.192
22 STAC 6769 SH3 and cysteine rich domain 0.189
23 PADI2 11,240 peptidyl arginine deiminase, type II 0.189
24 RCOR2 283,248 REST corepressor 2 0.179
25 IGF2BP2 10,644 insulin-like growth factor 2 mRNA binding protein 2 0.176
26 CDH3 1001 cadherin 3, type 1, P-cadherin (placental) 0.175
27 ZNF695 57,116 zinc finger protein 695 0.175
28 CLCN4 1183 chloride channel 4 0.172
29 MEX3A 92,312 mex-3 homolog A (C. elegans) 0.171
30 CBS 875 cystathionine-beta-synthase 0.171