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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Impact of cancer mutational signatures on transcription factor motifs in the human genome

Fig. 4

Demonstration of alteration correlation effect between creation and disruption probability: a Scatter plot of correlation between the creation and disruption probabilities for all 512 motifs across the 30 mutational signatures where each dot corresponds to a TF motif in one of the 30 signatures; b Difference of creation/disruption probabilities vs. motif entropy, with Hoxd8 highlighted in red and Pax9 in blue; c Boxplot of alteration probability absolute relative difference of Hoxd8 versus PAX9; d PWM logo of Hoxd8 (top) and alteration probability of Hoxd8 with respect to 96 trinucleotides (bottom); e PWM logo of PAX9 (top) and alteration probability of PAX9 with respect to 96 trinucleotides (bottom)

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