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Table 1 Characteristics of human subjects

From: Histamine H4 receptor gene polymorphisms: a potential contributor to Meniere disease

Variables

Control (n = 90)

Bilateral or Unilateral MD (n = 90)

P-value

Age, Mean (SD)

60 (12.3)

62 (12.8)

0.12

Gender, n (%women)

57 (63.0)

48 (52.5)

0.34

Ischemic heart disease, n (%)

6 (6.7)

9 (10.0)

0.68

Smoking, n (%)

9 (10.0)

7 (7.8)

0.68

Chronic obstructive pulmonary disease, n (%)

12 (13.3)

15 (16.7)

0.81

Rheumatoid history, n (%)

6 (6.7)

27 (30.0)

0.02*

Hypertension, n (%)

30 (33.3)

42 (40.0)

0.34

High cholesterol, n (%)

27 (30.0)

30 (33.3)

0.47

Diabetes, n (%)

15 (16.7)

39 (43.3)

0.01*

Asthma, n (%)

6 (6.7)

21 (23.3)

0.03*

Osteoarthritis, n (%)

6 (6.7)

48 (53.3)

0.01*

Thyroid disease, n (%)

3 (3.3)

3 (3.3)

1.00

Irritable bowel syndrome, n (%)

9 (10.0)

3 (3.3)

0.11

Hiatus hernia, n (%)

3 (3.3)

6 (6.7)

0.38

Gastroesophageal reflux disease, n (%)

21 (23.3)

24 (26.7)

0.55

Anxiety, n (%)

6 (6.7)

33 (36.7)

0.02*

Depression, n (%)

9 (10.0)

27 (30.0)

0.03*

  1. Age was compared by unpaired Student’s t test. Qualitative variables were compared by Chi-squared test. Asterisks represent statistical significance