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Table 1 Characteristics of human subjects

From: Histamine H4 receptor gene polymorphisms: a potential contributor to Meniere disease

Variables Control (n = 90) Bilateral or Unilateral MD (n = 90) P-value
Age, Mean (SD) 60 (12.3) 62 (12.8) 0.12
Gender, n (%women) 57 (63.0) 48 (52.5) 0.34
Ischemic heart disease, n (%) 6 (6.7) 9 (10.0) 0.68
Smoking, n (%) 9 (10.0) 7 (7.8) 0.68
Chronic obstructive pulmonary disease, n (%) 12 (13.3) 15 (16.7) 0.81
Rheumatoid history, n (%) 6 (6.7) 27 (30.0) 0.02*
Hypertension, n (%) 30 (33.3) 42 (40.0) 0.34
High cholesterol, n (%) 27 (30.0) 30 (33.3) 0.47
Diabetes, n (%) 15 (16.7) 39 (43.3) 0.01*
Asthma, n (%) 6 (6.7) 21 (23.3) 0.03*
Osteoarthritis, n (%) 6 (6.7) 48 (53.3) 0.01*
Thyroid disease, n (%) 3 (3.3) 3 (3.3) 1.00
Irritable bowel syndrome, n (%) 9 (10.0) 3 (3.3) 0.11
Hiatus hernia, n (%) 3 (3.3) 6 (6.7) 0.38
Gastroesophageal reflux disease, n (%) 21 (23.3) 24 (26.7) 0.55
Anxiety, n (%) 6 (6.7) 33 (36.7) 0.02*
Depression, n (%) 9 (10.0) 27 (30.0) 0.03*
  1. Age was compared by unpaired Student’s t test. Qualitative variables were compared by Chi-squared test. Asterisks represent statistical significance