Fig. 2
Mean methylation values of IC1 and IC2, measured by bisulfite pyrosequencing, in one BWS sample with mosaic upd(11p15.5)pat, indicated by a green diamond, and the two affected family members II.7 and III.1, indicated by orange and red symbols. The black box plots demonstrate methylation variation among 7 control samples without BWS. The bottom of the box indicates the 25th percentile, the top the 75th percentile. The median is represented by a horizontal line and the mean by an open diamond symbol within the box. Whiskers represent the observed methylation range in normal samples