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Table 1 Contingency table for two-locus combinations and phenotype

From: HiSSI: high-order SNP-SNP interactions detection based on efficient significant pattern and differential evolution

VariablesP(s(i,j))=1P(s(i,j))=0Total
y=caseaN1aN1
y=controlxaN0−(xa)N0
TotalxNxN
  1. x is the number of samples whose P(s(i,j)) take value 1. a has the same interpretation as x but restricted to cases.