Table 2 Genotype distributions of the miR-17-92 promoter polymorphisms between the ischemic stroke patients and the control group
Polymorphisms | Controls n = 397 (%) | Cases n = 398 (%) | OR (95% CI)†| P †| PBH |
|---|---|---|---|---|---|
rs1491034 | |||||
 TT | 100 (25.2) | 113 (28.4) | 1.00 (Ref) |  |  |
 TC | 209 (52.6) | 193 (48.5) | 0.89 (0.56~1.41) | 0.615 | 0.864 |
 CC | 88 (22.2) | 92 (23.1) | 1.16 (0.66~2.06) | 0.602 | 0.864 |
 TC + CC vs. TT |  |  | 0.96 (0.62~1.48) | 0.850 | 0.864 |
 CC vs. TC + TT |  |  | 1.26 (0.77~2.04) | 0.356 | 0.864 |
 T | 409 (51.5) | 419 (52.6) | 1.00 (Ref) |  |  |
 C | 385 (48.5) | 377 (47.4) | 1.06 (0.80~1.40) | 0.683 | 0.864 |
 HWE (P value) | 0.283 | 0.584 |  |  |  |
rs9301654 | |||||
 AA | 235 (59.2) | 280 (70.4) | 1.00 (Ref) |  |  |
 GA | 141 (35.5) | 112 (28.1) | 0.63 (0.41~0.97) | 0.037 | 0.111 |
 GG | 21 (5.3) | 6 (1.5) | 0.23 (0.07~0.78) | 0.018 | 0.09 |
 GA + GG vs. AA |  |  | 0.57 (0.38~0.87) | 0.009 | 0.068 |
 GG vs. GA + AA |  |  | 0.27 (0.08~0.89) | 0.032 | 0.111 |
 A | 611 (77.0) | 672 (84.4) | 1.00 (Ref) |  |  |
 G | 183 (23.0) | 124 (15.6) | 0.58 (0.40~0.83) | 0.003 | 0.045 |
 HWE (P value) | 0.980 | 0.163 |  |  |  |
rs982873 | |||||
 TT | 149 (37.5) | 167 (42.0) | 1.00 (Ref) |  |  |
 TC | 191 (48.1) | 171 (43.0) | 0.91 (0.59~1.39) | 0.660 | 0.864 |
 CC | 57 (14.3) | 60 (15.0) | 1.12 (0.63~2.00) | 0.705 | 0.864 |
 TC + CC vs. TT |  |  | 0.96 (0.64~1.43) | 0.838 | 0.864 |
 CC vs. TC + TT |  |  | 1.18 (0.69~2.01) | 0.550 | 0.864 |
 T | 489 (61.6) | 505 (63.4) | 1.00 (Ref) |  |  |
 C | 305 (38.4) | 291 (36.6) | 1.03 (0.77~1.36) | 0.864 | 0.864 |
 HWE (P value) | 0.737 | 0.141 |  |  |  |