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Table 2 Genotype distributions of the miR-17-92 promoter polymorphisms between the ischemic stroke patients and the control group

From: A functional polymorphism in the promoter of miR-17-92 cluster is associated with decreased risk of ischemic stroke

PolymorphismsControls
n = 397 (%)
Cases
n = 398 (%)
OR (95% CI)P PBH
rs1491034
 TT100 (25.2)113 (28.4)1.00 (Ref)  
 TC209 (52.6)193 (48.5)0.89 (0.56~1.41)0.6150.864
 CC88 (22.2)92 (23.1)1.16 (0.66~2.06)0.6020.864
 TC + CC vs. TT  0.96 (0.62~1.48)0.8500.864
 CC vs. TC + TT  1.26 (0.77~2.04)0.3560.864
 T409 (51.5)419 (52.6)1.00 (Ref)  
 C385 (48.5)377 (47.4)1.06 (0.80~1.40)0.6830.864
 HWE (P value)0.2830.584   
rs9301654
 AA235 (59.2)280 (70.4)1.00 (Ref)  
 GA141 (35.5)112 (28.1)0.63 (0.41~0.97)0.0370.111
 GG21 (5.3)6 (1.5)0.23 (0.07~0.78)0.0180.09
 GA + GG vs. AA  0.57 (0.38~0.87)0.0090.068
 GG vs. GA + AA  0.27 (0.08~0.89)0.0320.111
 A611 (77.0)672 (84.4)1.00 (Ref)  
 G183 (23.0)124 (15.6)0.58 (0.40~0.83)0.0030.045
 HWE (P value)0.9800.163   
rs982873
 TT149 (37.5)167 (42.0)1.00 (Ref)  
 TC191 (48.1)171 (43.0)0.91 (0.59~1.39)0.6600.864
 CC57 (14.3)60 (15.0)1.12 (0.63~2.00)0.7050.864
 TC + CC vs. TT  0.96 (0.64~1.43)0.8380.864
 CC vs. TC + TT  1.18 (0.69~2.01)0.5500.864
 T489 (61.6)505 (63.4)1.00 (Ref)  
 C305 (38.4)291 (36.6)1.03 (0.77~1.36)0.8640.864
 HWE (P value)0.7370.141   
  1. OR odds ratio, CI confidence interval, HWE Hardy-Weinberg equilibrium
  2. Adjusted by age, gender, hypertension, diabetes mellitus, TG, LDL-C, HDL-C, and TCH; PBH: P values corrected by Benjamin-Hochberg (B-H) method