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Table 1 Clinical characteristics of pan-glioma splicing types

From: Classification of glioma based on prognostic alternative splicing

 pST1(n = 153)pST2(n = 54)pST3(n = 173)pST4(n = 94)pST5(n = 20)pST6(n = 74)pST7(n = 97)Total(n = 154)
Clinical
 Age
 Median60573838504043.547
Survival (in months)
 Median (CI)13.5 (12.1,15.3)20.2 (17.9, 27.1)94.5 (55.5, NA)88.7 (68.4132.6)NA (32.1, NA)148.2 (74.5, NA)172.2 (76.1, NA)51.2 (44.6, 66.7)
Karnofsky score
 1001243017241786
 90212412331319113
 70–806911151031210130
  < 703136301347
Sex
 Female5426533893538253
 Male9927855673546355
Grade
 G204704474544214
 G3049675092540240
 G4153010000154
Histology
 Astrocytoma03568377157169
 Glioblastoma153010000154
 Oligoastrocytoma09392531819113
 Oligodendroglioma09303263758172
Molecular
 IDH Status
  Mutant9515188175996425
  WT140492153141233
 1P19Q
  Codel01232092885166
  Non-codel1475315074114612493
 TERT Expression Status
  Expressed127394020122782347
  Not.expressed25151327384615314
 ATRX Status
  Mutant8694534219195
  WT138487840165288460
 CHR7.Gain.CHR10.loss
  Gain.chr7&loss.chr109737140120151
  No.combined. CNA501715993197097505
CHR19.20.co.gain
  Gain.chr19/201963002030
  No.chr19/20.gain1284817093207097626
 MGMT Promoter
  Methylated512514778166394474
  Unmethylated712926164113160
Clusters
 Transcriptome Cluster
  CL49267111085
  MC66168610097
  NE5119906412110
  PN18372617469234
 Original Cluster
  Classical3900000039
  G-CIMP70100008
  IDHmut-codel01232092885166
  IDHmut-non-codel041276783111248
  IDHwt049216314194
  Mesenchymal5000000050
  Neural2600000026
  Proneural2900000029
 Pan-Glioma RNA Expression Cluster
  LGr120425179064139
  LGr230020632189
  LGr3941276810712237
  LGr412146206130197
 Pan-Glioma DNA Methylation Cluster
  LGm174181127352
  LGm2101205973827252
  LGm301141981466122
  LGm443144013065
  LGm55930120120104
  LGm612555110139