Table 2 Average time and costs associated with return of research findings incurred by the research program
From: Return of genetic and genomic research findings: experience of a pediatric biorepository
| Â | Median time (hours) | Unit cost or hourly | Total cost |
|---|---|---|---|
Curation of variants to present to committee | $40 | ||
 Manual re-interpretation of variant (Bioinformatician) | 0.5 | $50 | $25 |
 Chart review of participant medical records (Research coordinator) | 0.5 | $30 | $15 |
Return of Research Results Committee Review | |||
 Research staff time (Bioinformatician, Coordinator, Genetic Counselor) | 1 | $125 | $125 |
Verification of findings in research laboratory | $425 | ||
 Design and order primers, primer optimization, PCR (Technician) | 7 | $30 | $210 |
 Sample retrieval (Technician) | 0.5 | $30 | $15 |
 Sanger sequencing (SNV), qPCR (CNV) (Technician, reagents) |  | $200 | $200 |
Return of findings | $150 | ||
 Generating research report (Research coordinator) | 0.5 | $30 | $15 |
 Reporting research results to patient and family counseling (Genetic counselor) | 1 | $45 | $45 |
 Arranging clinical validation, reporting clinical results to patient and physician, documentation (Genetic counselor) | 2 | $50 | $100 |
 Total research costs per reportable finding without a genetic counselor |  |  | $560 |
 Total research costs per reportable finding with a genetic counselor |  |  | $750 |