Table 2 Gene pairs with the lowest adjusted p-value in breast cancer. Group 1: samples with the top 25% ΔPCC for the gene pair. Group 2: remaining samples
From: Finding prognostic gene pairs for cancer from patient-specific gene networks
Gene pair | Group 1 | Group 2 | Log-rank test | Cox PH | ||||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | statistic | p-value | adj. p-value | Hazard ratio | p-value | 95% CI |
LINC01234_MET | 76 | 974 | 39.06 | 4.11E-10 | 7.98E-07 | 3.36 | 2.56E-07 | 2.12 - 5.33 |
KRT5_SP1 | 129 | 921 | 36.26 | 1.73E-09 | 2.92E-06 | 2.62 | 1.71E-06 | 1.76 - 3.88 |
LINC01234_SERPINB5 | 41 | 1009 | 32.21 | 1.38E-08 | 1.95E-05 | 3.82 | 4.40E-06 | 2.15 - 6.79 |
CDH3_SP1 | 25 | 1025 | 31.24 | 2.28E-08 | 2.95E-05 | 7.94 | 3.70E-08 | 3.79 - 16.61 |
PTK6_SP1 | 55 | 995 | 30.58 | 3.20E-08 | 3.83E-05 | 4.55 | 1.21E-06 | 2.46 - 8.39 |
CLDN7_PIK3CA | 53 | 997 | 28.16 | 1.11E-07 | 1.23E-04 | 4.00 | 2.74E-07 | 2.36 - 6.80 |
KRT5_LINC01234 | 76 | 974 | 25.81 | 3.75E-07 | 3.89E-04 | 3.06 | 3.04E-06 | 1.91 - 4.91 |
LINC00636_SFN | 13 | 1037 | 23.95 | 9.89E-07 | 8.69E-04 | 6.98 | 2.33E-05 | 2.83 - 17.20 |
CCNH_NME1 | 83 | 967 | 23.90 | 1.01E-06 | 8.75E-04 | 2.62 | 1.95E-05 | 1.68 - 4.09 |
PIP_TRIM25 | 41 | 1009 | 23.50 | 1.25E-06 | 1.04E-03 | 2.86 | 4.01E-04 | 1.59 - 5.13 |