Table 1 The enriched GO terms (top 5) and KEGG pathways (top 5) of the DEGs
From: Competitive endogenous RNA (ceRNA) regulation network of lncRNAs, miRNAs, and mRNAs in Wilms tumour
Category | Term | ID | Count | FDR |
|---|---|---|---|---|
GO BP | response to mechanical stimulus | GO:0009612 | 11 | 0.001184756 |
GO BP | G1/S transition of mitotic cell cycle | GO:0000082 | 12 | 0.001333555 |
GO BP | cell cycle G1/S phase transition | GO:0044843 | 12 | 0.001784413 |
GO BP | muscle cell proliferation | GO:0033002 | 10 | 0.002607351 |
GO BP | mesenchymal cell differentiation | GO:0048762 | 9 | 0.009770918 |
GO CC | transcription factor complex | GO:0005667 | 10 | 0.01896361 |
GO CC | cyclin-dependent protein kinase holoenzyme complex | GO:0000307 | 4 | 0.01896361 |
GO CC | nuclear chromatin | GO:0000790 | 10 | 0.01896361 |
GO CC | nuclear transcription factor complex | GO:0044798 | 7 | 0.024102204 |
GO CC | Flemming body | GO:0090543 | 3 | 0.037639391 |
GO MF | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | GO:0000982 | 15 | 0.000130468 |
GO MF | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | GO:0001228 | 15 | 0.000130468 |
GO MF | proximal promoter sequence-specific DNA binding | GO:0000987 | 14 | 0.000902732 |
GO MF | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | GO:0001077 | 11 | 0.000902732 |
GO MF | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | GO:0001227 | 10 | 0.000902732 |
KEGG | Cell cycle | hsa04110 | 10 | 6.52E-06 |
KEGG | Small cell lung cancer | hsa05222 | 8 | 4.96E-05 |
KEGG | p53 signaling pathway | hsa04115 | 7 | 7.55E-05 |
KEGG | MicroRNAs in cancer | hsa05206 | 12 | 0.00013503 |
KEGG | Cellular senescence | hsa04218 | 9 | 0.000137065 |